Friday, July 6, 2012

Medical Book Reviews: Jayasinghe ECG Workbook and Robbins Basic Pathology 9th Edition


Elsevier Australia has kindly provided me with inspection copies of the following medical books.

1. ECG Workbook. (Professor) Rohan Jayasinghe.

Churchill Livingstone/Elsevier Australia, 2012. Paperback, 224 pages. RRP $59.95.

For many people ECGs are a bit like "Who's afraid of the big bad wolf”? In reality this includes quite a few of us. In medical school there are people who "just seem to get it" while others continue to struggle, and still "have their L-Plates on" after many years of medical experience.

This refreshing book is aimed at the clinical interpretation of ECGs. It is worthwhile to quote from the Preface written by the author:
“ECG Workbook provides an easy but systematic algorithm to follow when attempting to read an ECG. The exercises are aimed at training the reader to practise this algorithm repeatedly with different ECGs. The real-life clinical synopsis essentially links the ECG findings to the patient’s clinical context. This information guides the reader to make a clinical diagnosis with the help of the ECG findings, and then to decide on the optimal treatment or management plan. … It is hoped that by completing this workbook the reader will gain the required mastery to use ECG as a clinical diagnostic tool effectively and to make suitable management decisions with confidence.”

It is divided into three sections: 1. Basics of the ECG; 2. ECG-based diagnosis: pathology by ECG; and 3. ECGs and pathologies. There is also an Appendix listing the NYHA functional classes, and a detailed Index.

Beginning with Section 1, the pages are cleanly set out, with ample use of coloured headings, colour-shaded boxes for important points and plentiful use of explanatory diagrams. This chapter of 19 pages does indeed cover the basics in a very understandable fashion. It includes the cardiac cycle, the cardiac conduction system, ECG rate, scale and calibration, leads and direction of current travel, determining the cardiac axis and the causes of axis deviation, placement of electrodes and the difference between electrodes and leads, correlation of the leads to the region of the heart, and finally, reading the ECG. This includes a system for doing this together with the parameters of the normal ECG. To compliment rather than insult the author, for those craving a "Dummies' guide to the ECG", this is exactly the sort of thing you are looking for. The chapter is pitched at a good level and easy to follow, and puts the reader in a good position to approach the chapters on pathology that follow.

Section 2 is a chapter of 27 pages. It is set out in the same clean and comprehensive fashion as Section 1. An introduction on reading rate and abnormalities on an ECG is followed by a discussion of various pathologies, starting with different types of tachycardia and their management. Also discussed are bradyarrhythmias and bradycardia, heart block, abnormalities of the cardiac rhythm, normal and abnormal segments of the ECG, ventricular hypertrophy, myocardial infarction and ischaemia, other pathologies with mixed ECG changes, and finally pacemakers. All the common pathologies are discussed as well as some more obscure ones. Section 2 sets up the background for Section 3, which contains the ECG worksheets. After a brief introduction, 45 case studies follow.

The case studies are beautifully set out in two sections each. The first section contains an ECG on the left-hand page and a template for systematic interpretation on the right-hand page, including the various aspects of the ECG, further investigations and management. Before you start to feel that familiar rising sense of panic regarding "but what is the answer?", relax! The second section of each case study includes all the answers, and helps to drill the reader in the recommended approach to systematic interpretation, and helps to build confidence, as your answers can be directly compared to the recommended ones.

Being a paperback of around 250 pages, this book is very portable, and as well as being a workbook is also a handy reference, both in terms of Sections 1 and 2, but also the wide variety of ECGs included in Section 3. It is well-written, accessible and user-friendly. I would certainly recommend it, especially for those who feel a need to improve their ECG skills in a systematic fashion.



2. Robbins Basic Pathology. 9th Edition. Editors: Kumar, Abbas and Aster.

Elsevier Saunders, 2012. Hardback, 928 pages. RRP $103.99

Owners of the book can register it at studentconsult.com, which provides the facility to access the full text online, download images, add notes and bookmarks and to search across all individually owned Student Consult resources online. The online version of the book contains a special additional feature, "Targeted Therapy" boxes (stemming from an understanding of the molecular basis of disease), intended to provide examples of "bench-to-bedside" medicine.

When I was a medical student, our pathology 'Bible' was Robbins Pathologic Basis of Disease by Cotran, Kumar and Collins. I am the proud owner of the sixth edition and its little pocket handbook. This new book is the latest in a trusted and proud lineage. Many of the earlier products are also available via the Elsevier website. Back in those days material available on CD-Rom was considered pretty special and computer-based learning was fairly rudimentary. Since then there has been an explosion of Internet-based resources, and the editors are to be congratulated for "keeping up with the times". In one of the medical student tutorials that I take, students must report back and share with the rest of the class on Fridays the information that they have gleaned concerning the 'learning issues' for the week. Some students will bring their laptops and tablets and read off the screen. Such is the power of learning resources such as the online version of this book - provided there is an internet connection, students and health professionals can access this material wherever they are and use it as a resource in their everyday work.

The book contains 23 chapters over 870 pages, plus a detailed Index at the back. It is visually attractive, with a coloured strip at the top of each page making the chapters easy to distinguish. There is liberal use of coloured headings, diagrams, photographs, tables, orange "Morphology" boxes and blue "Summary" boxes. Even though the text is dense (as is to be expected in any serious medical textbook) the judicious use of colour, illustrations, boxes and space between the various elements makes it appear welcoming and engaging, as opposed to the forbidding nature of many 'old-fashioned' black and white textbooks. Each chapter has a "Chapter Contents" box in its introductory header, listing the key sections and their page numbers. This is a very handy navigation aid. There is also a bibliography at the end of each chapter.

The authors have strived to organise the chapters in such a way that the various groupings of pathologies and organ systems are logical. Some chapters do not have a specific attribution of authorship, whilst many of the chapters are written by other specialist contributors. As we have come to expect, the standard of the content is universally high. Many of the images will be familiar from earlier editions, but there are also many new ones, often showcasing the latest research discoveries.

These are the chapter headings:
1. Cell Injury, Cell Death, and Adaptations
2. Inflammation and Repair
3. Hemodynamic Disorders, Thromboembolism, and Shock
4. Diseases of the Immune System
5. Neoplasia
6. Genetic and Pediatric Diseases
7. Environmental and Nutritional Diseases
8. General Pathology of Infectious Diseases
9. Blood Vessels
10. Heart
11. Hematopoietic and Lymphoid Systems
12. Lung
13. Kidney and Its Collecting System
14. Oral Cavity and Gastrointestinal Tract
15. Liver, Gallbladder, and Biliary Tract
16. Pancreas
17. Male Genital System and Lower Urinary Tract
18. Female Genital System and Breast
19. Endocrine System
20. Bones, Joints, and Soft Tissue Tumours
21. Peripheral Nerves and Muscles
22. Central Nervous System
23. Skin.

In the interests of time and space and maintaining the attention of you the reader, it is probably not wise to attempt to review every single chapter, so I have selected one chapter as an example to demonstrate the general approach to layout and contents and the topicality and prescience of the authors in "walking the talk" as stated in the Preface: "This is an exciting time for students of medicine because the fundamental mechanisms of disease are being unveiled at a breathtaking pace. Pathology is central to understanding the molecular basis of disease, and we have tried to capture the essence of this new knowledge in the ninth edition ... We firmly believe that pathology forms the scientific foundation of medicine, and advances in the basic sciences ultimately help us in understanding diseases in the individual patient."

“Chapter 7: Environmental and Nutritional Diseases” examines diseases which are caused or influenced by environmental factors, including both the external environment and things that humans do to themselves (e.g., diet, drugs and alcohol). After the Introduction, the authors bravely enter into a discussion about the Health Effects of Climate Change and provide scientific evidence for the existence of climate change and list some of the serious consequences which are already occurring. The next key section deals with the Toxicity of Chemical and Physical Agents. This is divided into sub-sections (each with Morphology and Summary boxes) dealing with Environment Pollution - Air, Environmental Pollution - Metals, Effects of Tobacco, Effects of Alcohol, Injury by Therapeutic Drugs and Drugs of Abuse (oestrogens/contraceptives, paracetamol and aspirin; cocaine, heroin, marijuana and a list of "other illicit drugs"), and Injury by Physical Agents (trauma, thermal injury, hyperthermia, hypothermia, electrical injury and ionising radiation). Although one might perhaps argue that more substances could have been included, and more detail included on some of the given topics, a text such as this "cannot be all things to all men" and there are many other excellent references which do provide further information in these areas. However, what is included does serve an important function in "whetting the appetite" and encouraging readers to think beyond the superficial in terms of environmental injuries. The second key section is devoted to Nutritional Diseases and follows the same general layout principles. This covers malnutrition, eating disorders, vitamin deficiencies, obesity (another very topical inclusion) and concludes with short sections on Diet and Systemic Diseases and Diet and Cancer.

One small frustration is that, being an American text, the units of measurement may be different to those used in the Australian context e.g., Fahrenheit for temperature as opposed to Celsius.

The more that I looked at this book, the more that it was like opening a beneficent "Pandora's Box". It draws you in and engages your attention, and like those enraptured of the 'siren song' of old, you don't want to put it down. An odd thing to say about a text book, I know, but much of what the authors present to us about the underlying science of medicine is utterly fascinating. For those who wish that they had paid more attention in medical school, this is your "get out of jail free card", and for those embarking on the journey of learning, it is a marvellous road map. Highly recommended!

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